Study of the effect of ‘Vanari Gutika’ in Oligozosspermia to assess the spermatogenetic property of Vanari (Mucuna pruriens)

Title: Study of the effect of ‘Vanari Gutika’ in Oligozosspermia to assess the spermatogenetic property of Vanari (Mucuna pruriens)

          Dr. A. S. Kulkarni had submitted his dissertation in 1997 Year, for the P.G. degree M.D. Dravyaguna (Ayurvedic Pharmacology). His guide was Dr. S.G. Huparikar & research center was Tilak Ayurved Mahavidyalaya, Pune (M.S.) India.

          Dr. Kulkarni had done a clinical study of Vanari (Mucuna pruriens (L) DC.) for his vrushya property (To increase sperm count.) Dr. Kulkarni prepared ‘Vanarigutika’ according to the formula given by Yogaratnakar from the Vanari seeds.

          For randomized placebo -controlled clinical trials total 100 male Patients of oligospermia were selected.

Two different groups of 50/50 patients were made i.e.

Group A – 50 patients were selected for test drug treatment and

Group B – 50 patients were selected for placebo treatment for 3 months (90 Day). Oligospermia patients were divided in three subgroups as mild, moderate& severe oligospermia.

          Group A patients were treated with tablets of Vanarigutika 1 bd with milk after meals for 3 months & Group B patients were treated with placebo –rice flour tablets 1 bd with milk for the same period & time.

          The semen analysis was carried out before treatment i.e. 1^st day & after treatment last day.

          The research work was concluded as follows –

Vanarigutika ( From –Yogaratnakar)  1  BD with milk after meals for 3 months,showed moderate improvement in spearm count & sperm motility

          This analysis revealed that the significant improvement is seen in the mean sperm counts with the ‘Vanarigutika’ treated patients having mild & moderate categories.

          The overall improvement in the sperm count with severe category patients was not significant.

          Group B (Placebo treated) patients have shown no significant improvement in their sperm count.

          An improvement in the seminal volume, viscosity & motility of sperms from Group A specially severe category.

          In short, Vanarigutika showed a beneficial effect on sperm count in the cases of oligospermia, hence it is confirmed that Vanari (Mucuna pruriens (L) DC.) which is a chief ingredient of this drug is having a stimulating effect on spermatogenesis.